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This is a lesson about the basic requirements for human survival. Learners will use an online, multimedia module, in which they make changes to the ecosystem and draw conclusions about the biologic conditions that are necessary for human survival. The lesson models scientific inquiry using the 5E instructional model and includes teacher notes, prerequisite concepts, common misconceptions, student journal and reading. This is lesson 1 in the Astro-Venture Biology Training Unit that was developed to increase students' awareness of and interest in astrobiology and related STEM careers. The lessons are designed to be used with the Astro-Venture multimedia modules.