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In this lab activity, student teams hypothesize which source has a greater becomes CO² concentration: their breath, auto exhaust, or air in the classroom. They test gas samples from each of these sources, plot data, and hypothesize about the respective role engine exhaust and animal respiration play in contemporary climate change. The lab procedures require Bromthymol Blue indicator solution (BTB), household ammonia, vinegar, and balloons. Links to videos supporting the investigations are provided. This activity is supported by a textbook chapter, "How is Carbon Dioxide Measured?," part of the unit, Climate Change, in Global Systems Science (GSS), an interdisciplinary course for high school students that emphasizes how scientists from a wide variety of fields work together to understand significant problems of global impact.